Use of GRA6-Derived Synthetic Polymorphic Peptides in an Immunoenzymatic Assay To Serotype Toxoplasma gondii in Human Serum Samples Collected from Three Continents
نویسندگان
چکیده
منابع مشابه
Selection of polymorphic peptides from GRA6 and GRA7 sequences of Toxoplasma gondii strains to be used in serotyping.
The evaluation of Toxoplasma gondii isolates obtained from geographical environments other than Europe and North America revealed the existence of atypical strains that are not included in the three archetypal clonal lineages (lineages I, II, and III). GRA6 and GRA7 are polymorphic genes that have been used for the genotyping of Toxoplasma. The coding regions of GRA6 and GRA7 from 49 nonarchety...
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Toxoplasma gondii infection results in co-option and subversion of host cellular signaling pathways. This process involves discharge of T. gondii effector molecules from parasite secretory organelles such as rhoptries and dense granules. We report that the T. gondii polymorphic dense granule protein GRA6 regulates activation of the host transcription factor nuclear factor of activated T cells 4...
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In order to investigate whether previous findings of ubiquitous skin papillomavirus infection in Caucasians apply to populations from other parts of the world, skin swab samples from Bangladesh, Japan, Ethiopia and Zambia were analysed in parallel with Swedish samples. The prevalence of HPV DNA in the material from Bangladesh was 68 %, Japan 54 %, Ethiopia 52 %, Zambia 42 % and Sweden 70 %. A g...
متن کاملDetection of antibodies to the 97 kDa component of Toxoplasma gondii in samples of human serum.
This study was carried out to investigate the immune response against 97 kDa (p97) molecular marker of Toxoplasma gondii that has been characterized as a cytosolic protein and a component of the excreted-secreted antigens from this parasite. A total of 60 serum samples from patients were analyzed by enzime-linked immunosorbent assay and Western blot for toxoplasmosis. These samples were organiz...
متن کاملEvaluation of gender-related differences in response to oxidative stress in toxoplasma gondii positive serum
Purpose: Toxoplasma gondii (T. gondii) is the causative agent of toxoplasmosis. It infects up to one third of the human population. The aim of this study was to evaluate the effects of T. gondii infection on induction of oxidative stress in serum of infected men and women. Materials and Methods: This case-control study was carried out on 150 individuals who had referred to our center ...
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ژورنال
عنوان ژورنال: Clinical and Vaccine Immunology
سال: 2008
ISSN: 1556-6811,1556-679X
DOI: 10.1128/cvi.00186-08